Toxin A=enterotoxin→alters fluid secretion
Toxin B=cytotoxin(more potent than Toxin A)→cause ☆apoptosis in a variety of cell types via actin depolymerization
(Toxins inactivate Rho-regulatory proteins which is involved in actin cytoskeletal structure maintenance. The result is ☆loss of cytoskeleton integrity, leading to cell rounding/retraction, disruption of intercellular tight junctions, and increased paracellular intestinal fluid secretion (eg, watery diarrhea))
gastrointestinal
microbiology
Optimized studying based on the forgetting curve vastly improves memorization. - What is reminDO?
Memorize
