deficient enzyme in maturity-onset diabetes of the young(MODY)

characteristics

(若年発症成人型糖尿病)

glucokinase(production of glucose-6-phosphatase from glucose)

mild hyperglycemia that often worsens with pregnancy-induced insulin resistance
☆can maintain very good glycemic control with dietary modification only

patients with MODY are typically younger and nonobese, and the condition is nonprogressive, even without the treatment
not associated with an elevated risk of long term diabetic complications

endocrinology biochemistry UWorld