☆CD55/59➖RBCs on flow cytometry
Chronic hemolysis with breakdown of iron-containing erythrocytes can also lead to iron deposition in the kidney (☆hemosiderosis), which can interfere with proximal tubule function and cause interstitial scarring and cortical infarcts. The hemosiderosis combined with microvascular thrombosis can increase the risk of CKD.
+ thrombosis at atypical site(hepatic, portal, cerebral), pancytopenia
eculizumab(inhibits terminal complement formation)
pharmacology
hematology
UWorld
Optimized studying based on the forgetting curve vastly improves memorization. - What is reminDO?
Memorize
