staphylococcal toxic shock syndrome(TSS)
pathophysiology, etiology, symptoms

TSST-1(superantigen) binds to ☆MHCⅡ and T-cell receptor, resulting in polyclonal T-cell activation

prolonged use of vaginal tampons or nasal packing

fever, desquamation, shock, end organ failure, ↑AST, ↑ALT, ↑bilirubin

microbiology immunology UWorld