fetal erythropoeiesisYolk sac (3–8 weeks)
Liver (6 weeks–birth)
Spleen (10–28 weeks)
Bone marrow (18 weeks to adult) hematologyembryology Jul 1, 2020, 8:25 AM HirotoShishido
what embryonic structures give rise to SVC/IVCRight common cardinal vein and right anterior cardinal vein→ SVC
Posterior, subcardinal, and supracardinal veins→ IVC cardiologyembryology Jun 27, 2020, 5:12 AM HirotoShishido
Pierre Robin sequencemicrognathia, glossoptosis, cleft palate, airway obstruction(☆improve with prone position)
☆A sequence occurs when a single developmental defect causes a cascade of additional malformations. embryologypediatricsUWorld May 13, 2020, 10:15 PM HirotoShishido
hypospadias, epispadias
pathogenesishypo→ failure of urogenital folds(penile urethra, labia minora) to fuse
epi→ faulty positioning of genital tubercle (glans penis, glans clitoris)
thyroid
embryologythyroid arises from floor of primitive pharynx and descends into neck through thyroglossal duct embryologyendocrinology Jun 29, 2019, 7:31 AM HirotoShishido
two types of cysts on the neck(birth defect)thyroglossal duct cyst→presents as an anterior midline neck mass which ☆moves with swallowing
the reason why phenytoin trigger neural tube defectchronic phenytoin use changes PH in the gut into 10-12, which reduces folate uptake(optimal PH for folate is 5〜5.5) pharmacologyembryologyOBGY Apr 27, 2019, 12:33 AM HirotoShishido
sinus hornright sinus horn→openings of superior vena cava and inferior vena cava
aortic arches
①when does it exist ②where does it come from ③what Ⅲ,Ⅳ,Ⅵ develop into①weeks 4-6
②sprout from aortic sac
③Ⅲ→common carotids
Ⅳ→lt aortic arch
rt right subclavian
Ⅵ→pulmonary arteries
(+left→ductus arteriosus) embryology Apr 19, 2019, 6:05 AM HirotoShishido
4 structure which is fused after the lateral foldingdorsal aortae→aortic sac
heart tubes→primitive heart tube
vitelline veins→sinus venosus
pericardial cavities cardiologyembryology Apr 19, 2019, 5:57 AM HirotoShishido
heart before the lateral folding
bloodflowblood comes from vitelline vein go through heart tube, and then dorsal aorta cardiologyembryology Apr 19, 2019, 5:38 AM HirotoShishido