3 urinary incontinencestress incontinence 腹圧性失禁
urgency incontinence 切迫性失禁
(mixed incontinence stress and urgency are mixed 混合性失禁)
overflow incontinence 溢流性失禁 urology May 11, 2019, 3:39 AM HirotoShishido
BPH symptoms(start when prostatic urethra obstructed)
dribbling(weak stream of urine)
dysuria(pain during urination)
have to strain when urinating
hesitensy(trouble initiating urination)
nocturia reproductiveurology May 11, 2019, 1:41 AM HirotoShishido
benign prostatic hyperplasia(BPH) pathogenesis(5α-redactase convert testosterone into dihydrotestosterone,DHT)
after 30yo,testosterone production decline by 1% every year
meanwhile,5α-redactase increase with age
eventually, more DHT allows luminal and basal cells in the prostate to keep growing and multiplying urologyreproductive May 11, 2019, 1:30 AM HirotoShishido
which cell does secrete inhibin B, androgen binding protein(ABP), and Müllerian inhibitory factor(MIF) in male reproductive system・Sertoli cells
inhibin B which inhibit FSH
ABP allows testosterone to cross blood-testis barrier
(☆if dysfunctioning, low concentration of testosterone in the seminiferous tubule and normal circulating teststerone level can be seen(as long as hypothalamus-pituitary-gonad axis are normally functioning)
MIF that suppress development of paramesonephric ducts
