how is fatty acid degradation regulatedmalonyl CoA inhibits carnithine acyltransferase,
preventing the transfer of acyl groups into the mitochondria biochemistryUWorld HirotoShishido
infertility in cystic fibrosisimproper development of the ☆mesonephric (Wolffian) duct system, which most often leads to a defective vas deferens biochemistry HirotoShishido
cystinuria
pathophysiologya defect in amino acid reabsorption in the ☆proximal tubule that leads to defective reabsorption of cystine, ornithine, lysine, and arginine(COLA)
function of NADPH☆anabolic processes(eg steroid and fatty acid synthesis)
respiratory burst
cytochrome P-450 system
glutathione reductase
aldose reductase(glucose→ sorbitol) biochemistry HirotoShishido
for which enzyme does thiamine(vB1)/biotin(vB3) serves as a cofactor?vB1
①α-ketoglutarate dehydrogenase
②Transketolase
(thiamine deficiency can be diagnosed if ☆baseline erythrocyte transketolase activity is low but increase after addition of thimine pyrophosphate)(HMP shunt→glycolysis/gluconeogenesis)
③Pyruvate dehydrogenase (to acetyl CoA)
the difference between ornithine transcarbamylase deficiency and orotic aciduriaincreased orotic acid in urine and blood for both
OTC→XR, hyperammonemia, no megaloblastic anemia
treatment→ ☆protein restriction(for urea cycle disorders)
from what amino acid is thyroid hormone made?Phenylalanine is a precursor to tyrosine, and tyrosine residues are needed to create thyroid hormone biochemistryendocrinology HirotoShishido
which site of tRNA is amino acid bound to?Amino acids are covalently bound to the 3′ CCA of tRNA molecules.
(This reaction is catalyzed by aminoacyl-tRNA synthetase.)
