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①lytic phase,mixed phase,sclerotic phase ②usually asymptomatic, but can result in weak or misshapen bone which can lead to fracture,nerve compression ③osteoporosis medication(except for teriparatide which can increase the risk of osteosarcoma)as antiresorptive drug surgery(for deformities,fractures,impinged nerve)
musculoskeletal
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HirotoShishido
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