β2 receptor effect
what should be careful about with the patient who has both DM and hypertension

(protein kinase A blocks ☆myosin light chain kinase in smooth muscle)

smooth muscle cells relaxation
bronchodilation
decrease GI motility
¥decrease uterine tone
secretion of aquaous humor
increase cellular K+ uptake(↓serum pottacium)
☆increase insulin(⇔α2)
☆increase glucose via liver
☆release of glucagon via pancreous

there's the possibility of hypoglycemia unawareness who use both nonselective β blocker and insulin(or sulfonylureas)

endocrinology neurology pharmacology