type Ⅲ hypersensitivity
fever, (★)arthritis, itchy rash during the prodromal period of the infection 1-2weeks after antigen exposure
•Antivenom or antitoxin containing animal proteins or serum
•Medications, most frequently antibiotics (e.g., ★penicillin, amoxicillin, cefaclor, trimethoprim-sulfamethoxazole, ☆chimeric monoclonal antibodies→ rituximab, infliximab)
•Infections: ¥Hepatitis B virus
☆scattered areas of fibrinoid necrosis and neutrophil infiltration in small blood vessels
immunology
microbiology
UWorld step2CK
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Memorize