must be given via intravenous or subcutaneous/ intramuscular routes ×oral
mAbs are ☆not eliminated by hepatic or renal clearance, but are instead removed from the body in 2 primary ways:
・Target-mediated drug clearance: mAbs directed against cell surface antigens undergo internalization upon binding to their targets, removing them from the circulation
・Nonspecific clearance: Immunoglobulins are constitutively taken up by reticuloendothelial macrophages and vascular endothelial cells.
immunology
pharmacology
UWorld
Optimized studying based on the forgetting curve vastly improves memorization. - What is reminDO?
Memorize
