fatigue and ★pruritus (very severe especially at night)
★cutaneous xanthomas and xanthelasmas
(ascending cholangitis (★narrowing and dilatations of bile ducts that may result in “beading”, both intrahepatic and extrahepatic bile ducts) is associated with PSC and not with PBC)
autoimmune conditions
(eg, ☆Sjogren syndrome, Hashimoto thyroiditis, rheumatoid arthritis, celiac disease).
gastrointestinal
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