central DI
desmopressin, hydration
nephrogenic DI
☆hydrochlorothiazide(HCTZ), NSAIDs(indomethacin)→↑aquaporin2, amiloride→lithium, hydration, dietary salt restriction
Thiazides appear to reduce renal water losses in NDI by inducing a mild volume depletion that ☆increases sodium and water reabsorption in the proximal tubule.
Infants with NDI cannot freely replace ongoing water losses, and early treatment is essential for preventing associated mental and physical growth retardation.
endocrinology
UWorld
Optimized studying based on the forgetting curve vastly improves memorization. - What is reminDO?
Memorize