renal dysfunction can lead to ☆metabolite accumulation and opioid toxicity
Morphine-6-glucoronide is particularly
responsible for toxicity, acting as a more potent mu opioid receptor agonist than morphine itself.
→ fentanyl or hydromorphone is often preferred as these drugs are predominantly
hepatically cleared
neurology
pharmacology
UWorld
Optimized studying based on the forgetting curve vastly improves memorization. - What is reminDO?
Memorize
