what regular activity is the most important and recommended in the patient with diabetes mellitus☆daily foot inspection
→clinicians are advised to complete comprehensive foot examinations annually on all diabetic patients, who should in turn be instructed on prophylactic foot care for trauma or infection (eg. wash and closely examined daily, change fitting socks daily, trim nails to the shape of the toe) endocrinologyUWorld SIM1 May 25, 2020, 10:00 AM HirotoShishido
patiromer
mechanism, clinical use, adverse effecta nonabsorbable cation exchange resin that binds colonic potassium in exchange for calcium, trapping potassium within the resin where it is then excreted in the feces.
often used for treatment of ★chronic hyperkalemia. (however, onset of action takes several hours, so it is not recommended as monotherapy in acute hyperkalemia)
GI disturbance, hypercalcemia, hypokalemia, hypomagnesemia
hypothyroidism and T3synthetic T3 (liothyronine) is not recommended for the routine treatment of hypothyroidism, as it has a short half-life and patients can experience wide fluctuations in plasma T3 levels
ADH V1 and V2 receptorsV2 reabsorb water causing concentration of urine, dilution of body fluids(by inserting aquaporins into collecting duct)
V1 cause contraction of vascular smooth muscles leading to an increase in total peripheral resistance pharmacologyendocrinology May 29, 2019, 12:27 AM HirotoShishido
three types of chronic gout drugsxanthine oxidase inhibitors
-allopurinol
(oxypurinol)
-feboxostat
uricosuric medication
-probenecid
-sulfinpyrazone(not used in Japan)
→☆dosage adjustment for penicillin
(because organic anion transporter(OAT) is inhibited in the proximal convoluted tubule, and inhibits secretion of penicillin)
hormones associated with intracellular receptorsteroids hormones(aldosterone, cortisol,gonadotropin),
vitamin D (cholecalciferol,ergocalciferol,calcitriol)
thyroid hormone endocrinology Jun 29, 2019, 1:18 AM HirotoShishido
two diseases the risk of which is increased by Hashimoto diseaseceliac disease
type Ⅰ diabetes mellitus endocrinology Jun 27, 2019, 4:05 AM HirotoShishido
