patiromer
mechanism, clinical use, adverse effecta nonabsorbable cation exchange resin that binds colonic potassium in exchange for calcium, trapping potassium within the resin where it is then excreted in the feces.
often used for treatment of ★chronic hyperkalemia. (however, onset of action takes several hours, so it is not recommended as monotherapy in acute hyperkalemia)
GI disturbance, hypercalcemia, hypokalemia, hypomagnesemia
sacubitril
mechanisminhibit neprilysin
can be used in combination with valsartan
(Sacubitril is found to decrease mortality and morbidity of patients with chronic heart failure with decreased ejection fraction) pharmacologycardiovascular HirotoShishido
the difference of mechanism between paclitaxel and vinca alkaloidspaclitaxel(TAXanes)→ ☆hyperstabilize polymerized microtubules in M phase so that mitotic spindle cannot break down(anaphase cannot occur)
(TAX STABILIZE the society)
The diagnosis can be confirmed with serologic testing for B henselae. Although generally self-limited, empiric antibiotic therapy with ☆azithromycin may prevent dissemination of infection to the liver, spleen, or nervous system.
systematic approach to stepping up medications for asthmaSABA(short acting albuterol inhaler), then low-dose ICS(inhaled corticosteroids), then moderate-dose ICS, then high-dose ICS, then LABA(long), and lastly oral corticosteroids.
used as an antitussive in adult and pediatric patients with a persistent cough after ruling out other potential pathologies (COPD, asthma, allergies, sinusitis) pharmacologyrespiratory HirotoShishido
OCTs contraindications☆smokers>35yo(↑risk of cardiovascular event)
