Post : HirotoShishido

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prenatal screening for group B streptococcus

characteristics of the bacteria GBS colonization by vaginal-rectal culture at 35-37 weeks gestation is recommended to identify colonized woman who require ★intrapartum penicillin/ampicillin to prevent neonatal GBS sepsis, pneumonia and meningitis

women with heavy colnization (eg. asymptomatic bacteriuria) needs ampicillin (★)regardless of screening status or rectovaginal culture results

GBS= streptococcus agalactiae
Produces ☆CAMP factor, which ☆enlarges the area of hemolysis formed by S aureus.
microbiology UWorld UWorld step2CK Feb 2, 2020, 3:32 AM   HirotoShishido

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TAP protein
function TAP(transporter associated with antigen processing) protein transports some of the peptide fragments degraded by proteasome into the endoplasmic reticucum and load onto ☆MHC class Ⅰ molecules

genetic mutation affecting MHC claps Ⅰ polypeptide complex expression(bare lymphocyte syndrome type Ⅰ)
→ulcerative glanulomatous skin lesions and frequent respiratory infeltions ☆despite normal lymphocyte and immunoglobulin levels
immunology UWorld Feb 13, 2020, 9:50 AM   HirotoShishido

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