(remains one of the most commonly used inhaled anesthetics worldwide)
hepatotoxicity (fulminant hepatitis with a 50% fatality rate)
→ causes the liver to rapidly atrophy and appears ☆shrunken on autopsy
(histologically, centrilobular necrosis is indistinguishable from acute viral hepatitis)
☆↑sesum aminotransferase levels,
prolonged prothrombin time
anesthesiology
pharmacology
UWorld
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