nonradioactive iodide(eg ☆potassium iodide) can competitively inhibit radioactive iodine-131 ☆from entering thyroid follicular cells (+release of T4+T3)
(large increases in serum iodide levels also inhibit iodine oiganification(Wolff-Chaikoff effect) and reduce thyroid hormone release)
(iodide=anion of iodine)
PTU(propylthiouracil) inhibit iodine organification, but potassium iodide promotes this effect more rapidly and efficiently
endocrinology
UWorld
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