HIV genome contains three major genes
env (gp120 and gp41):
gp120(surface)-attachment to host CD4+ T cell.
gp41(transmembrane)-fusion and entry.
gag (p24 and p17):
capsid and matrix proteins, respectively.
pol:
☆Reverse transcriptase, Integras, Protease; RIP “Pol” (Paul)
protease cleave gag and pol polyprotein products(gag-pol) into individual HIV ☆enzyme, and structural proteins
microbiology
UWorld
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