physiologic insulin secretion1-2 hr peak
no LAG
Lispro, Aspart, Glulisine
(→ regular(2-4hr) available ☆iv, im → NPH(4-12hr)→detemir(3-9hr, lasts up to 24hr)→)
glarGINE→no peak(long acting, lasts about 24hr)
insulin degludec, concentrated glargine with duration of action>24hr
physiologic insulin secretion can be approximated by a combination of ☆long-acting and rapid-acting insulin analogs (ie, basal-bolus regimen).
(glargine once daily plus lispro before each meal) endocrinology卒試UWorld HirotoShishido
→→
☆pralidoxime(regenerates AChE if given early)(PAM)(☆should be given only after atropine because it can cause transient acethylcholinesterase inhibition) pharmacologyUWorld卒試 HirotoShishido
bone tumors which manifest bone pain worsing at nightosteoid osteoma
