Typical signs and symptoms include diarrhea and abdominal pain, followed 2 or more weeks later by myalgias, ☆conjunctival hemorrhages, ☆★periorbital edema, and eosinophilia
leukocyte adhesion deficiency type1
defect, presentationdefect in LFA-1 integrin(☆CD18) protein on phagocytosis
→impaired ☆migration and chemotaxis
recurrent skin and mucosal bacterial infections(eg. omphalitis, ★periodontitis)
delayed (>30days) separation of umbilical cord, absent pus, ☆persistent leukocytosis due to leukocyte not being able to migrate out of the blood vessels immunologyNBMEUWorld step2CK Nov 24, 2019, 6:28 AM HirotoShishido
blindness caused by nematodesonchocerca volvulus(FLY guy→transmitte by ☆black fly) →river blindness, black skin nodules
ivermectin