first line for multiple myeloma for both an induction therapy and chemotherapy alone
(HSCT eligible : induction therapy followed by autologous HSCT
HSCT ineligible: chemotherapy alone)
Proteasome inhibitor→accumulation of toxic intracellular proteins, and an excess of proapoptotic proteins
Both of these effects induce ☆apoptosis of the malignant plasma cells.
hematology
UWorld
Optimized studying based on the forgetting curve vastly improves memorization. - What is reminDO?
Memorize