M avium(MAC)
severe cases arise in patients with AIDS
Most patients with disseminated MAC infection have nonspecific symptoms (eg, fever, weight loss, diarrhea).
Widespread involvement of the reticuloendothelial system often causes ☆anemia, ☆hepatosplenomegaly, and/or elevated alkaline phosphatase and lactate dehydrogenase.
Bone marrow biopsy with histopathology typically shows evidence of granulomata composed of ☆foamy epithelioid cells and multinucleated Langhans cells.
microbiology
UWorld
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