development of a new systolic murmur that resolved following revascularization in patients with myocardial infarction(MI)

Myocardial infarction can cause ischemia of the papillary muscle and the adjacent LV wall on which it is mounted.

This results in hypokinesis and outward ☆displacement of the ☆papillary muscle, creating increased tension on the attached chordae tendineae and preventing complete closure of the corresponding mitral valve cusp.

Timely restoration of adequate blood supply with coronary revascularization restores papillary muscle and LV wall motion, often leading to resolution of the MR.

cardiology UWorld