"respiratory" Post in this tag
measles
possible sequelae
subacute sclerosing panencephalitis (SSPE, occuring years later)
encephalitis
acute dissiminated encephalomyelitis
multinucleated giant cell pneumonia
otitis media
respiratory
microbiology
HirotoShishido
how corticosteroids work for asthma
by inhibiting NF-κB it can suppress transcription of many cytokines
mast cells→ ↑annexin A1→ inhibit phospholipase A2 →synthesis of leukotrienes & prostagrandines
Th2 cells→ ↓IL-4,5→ ↓activity of mast cells & eosinophils
respiratory
immunology
pharmacology
HirotoShishido
steroids used for asthma
①inhaled corticosteroids
(MOM playing FLUTe→)mometasone, fluticasone
(best BUD, SON→)budesonide
②(2 chrom plating→)cromolyn,nedocromil
prevent release of inflammatory mediaters from mast cells
very short, rarely used
③(omega, lizard→)omalizumab
very expensive
pharmacology
respiratory
HirotoShishido
sympathomimetics and muscarinic antagonists for obstructive lung disease
(2 headed bee→)β2 agonists
short acting: (Albert Einstein→)albuterol
long acting: (salmon, formal wear→)salmeterol, formoterol→ can be used for COPD
(3 armed musketeer→)M3 antagonist
(tropical tree, tie, rat→)tiotropium, ipratropium
respiratory
pharmacology
HirotoShishido
respiratory development stage2
canalicular 菅状期
week16-26
terminal bronchioles develop into respiratory bronchioles
and then, pulmonary capillaries start to form
after week24, the first primitive alveoli is formed
embryology
respiratory
HirotoShishido
SVC syndrome symptoms
facial plethora(flushing)
JVD,upper extremity edema
if obstruction is severe→can increase intracranial pressure(ICP)
respiratory
HirotoShishido
ground glass opacities
non-specific sign with a wide etiology
including
opportunistic infection(e.g. pneumocystis,CMV,RSV)
chronic interstitial disease(interstitial pneumonia)
acute alveolar disease(ARDS)
respiratory
radiology
HirotoShishido
histology of pulmonary hamartoma
= pulmonary chondroma
islands of mature ☆hyaline cartilage, fat, smooth muscle and clefts lined by respiratory epithelium
respiratory
UWorld
HirotoShishido
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