☆Receptor inactivation & internalization by arrestins
Arrestin is a protein that prevents further G protein activation and links the receptor complex to clathrin, facilitating receptor endocytosis and depletion from the cell surface.
other examples of tachyphylaxis → bronchodilator(β-adrenergic), nitrates(decrease in NO production), desmopressin (depletion of vWF from endotgelial storage sites), barbiturates (induction of CYP450 enzyme)
pharmacology
UWorld
Optimized studying based on the forgetting curve vastly improves memorization. - What is reminDO?
Memorize
