symptom management for hyperthyroidismpropranolol is indicated(β-blocker)
The symptoms of hyperthyroidism are due primarily to increased β-adrenergic outflow stimulated by excessive thyroid hormone release. endocrinologypharmacology HirotoShishido
the treatment for pregnant women with DVT at less than 37 weeks gestationlow molecular weight heparin (LMWH), such as ☆enoxaparin, is preferred over unfractionated heparin pharmacologyOBGYhematology HirotoShishido
treatment for phencyclidine, cocainePCP→benzodiazepine
macrolides
mechanism of resistance☆'methylation of the 23S rRNA' in resistant bacteria diminishes the binding of macrolides. microbiologypharmacology HirotoShishido
biological therapy for IBDanti TNF-α(infliximab)
anti IL-12/23(ustekinumab)
anti JAK(tofacitinib)
anti S1P(sphingosine 1 phospate)(ozanimod)→affect liver and heart
anti α4β7 integrin(vedolizumab) pharmacologygastrointestinal HirotoShishido
what patient is contraindicated in the use of β-blockercocaine user
By blocking presynaptic reuptake of norepinephrine and increasing release of catecholamines from the adrenal glands, cocaine results in a high degree of adrenergic activity
→unopposed α adrenergic receptor agonist activity
→ increase in hypertension and further ischemia in the coronary arteries cardiovascularpharmacology HirotoShishido
management of pain in the patients with chronic pancreatitisoctreotide(somatostatin analog)
which antiarrythmics increase the toxicity of digoxin?quinidine
will increase the level of effect of digoxin by basic drug competition for renal tubular clearance pharmacologycardiovascular HirotoShishido
symptoms develop on Monday with re-exposure, due to loss of tolerance. The most severe consequence occurs when compensatory vasoconstriction is unopposed in critical areas such as the coronary vessels, leading to nonatherosclerotic-related cardiac ischemia cardiovascularpharmacology HirotoShishido
