"dermatology" Post in this tag
the most common skin cancer
histopathology
BCC (basal cell carcinoma)
・fresh colored shiny lesion
・waxy,pink,pearly nodules with central telangiectasias
・palisading nuclei
dermatology
HirotoShishido
what is defective in xeroderma pigmentosum
nucleotide excision repair
occurs in G1 phase of cell cycle
(mismatch repair→Lynch syndrome,
occurs predominantly in S phase)
dermatology
biochemistry
HirotoShishido
annular erythema
annular erythema(環状紅斑)
MIICOが環ぐる
・Malignancy(GLUcagonoma→necrotic migratory erythema)
・Idiopathic
・infection(rheumatic fever→erythema marginatum)
・COllagen disease(Sjogren, SLE)
dermatology
HirotoShishido
caterpillar dermatitis
treatment
2% of caterpillars are toxic
Apply a piece of adhesive tape to the affected areas and pull the tape off immediately
dermatology
HirotoShishido
psoriasis histopathology
acanthosis(epidermal hyperplasia) with parakeratotic scaling(retention of nuclei in staratum corneum)
↑stratum spinosum
↓stratum granulosum
dermatology
HirotoShishido
psoriasis mnemonic
SMAP AKB48
Silvery-white scaling plaques,topical corticoSteroids
Munro microabscesses (neutrophils)
Auspitz sign (pinpoint bleeding when scales are scraped off)
PUVA(phototherapy)
arthritis(DIP関節)
koebner phenomenon(正常部位を刺激すると病変部位と同様の変化を起こす isomorphic response)
(b)vitamin D3→ ¥calcipotriene, callitriol
48 ターンオーバー45→3日(45+3)
dermatology
Amboss level4
HirotoShishido
More