tumor marker/ histology of the most common ovarian neoplasm in adolescentsdysgerminoma(equivalent to male seminoma)
(vs most common in young female→ mature cystic teratoma)
All four hormones share the same α subunit; it is their β subunit that confers functional specificity.
Treatment options include the administration of drugs that act like FSH and LH.
☆Menotropin (human menopausal gonadotrophin) therapy ☆mimics FSH and triggers the formation of a dominant ovarian follicle.
When the follicle appears mature, exogenous human chorionic gonadotropin (hCG) is administered→ simulate ☆LH surge reproductiveUWorld HirotoShishido
Clomiphene citrate
mechanism, indicationSERM that acts as an antiestrogen=( blocks negative feedback on hypothalamus), which leads to increased secretion of GnRH and ultimately to increased testosterone
medical abortionmifepristone (progesterone antagonist to make the uterus an uninhabitable/unsustainable environment for the fetus)
+ Misoprostol (prostaglandin E1 agonist) is taken 24–48 hours later; this drug causes uterine contraction and expulsion of the uterine contents OBGYreproductive HirotoShishido
ovarian neoplasm which manifest postmenopausal bleedingsex cord stromal tumor
benign→ thecoma(may produce estrogen), ☆Sertoli-Leydig cell tumor (may produce androgens →virilization
(eg, hirsutism, male pattern baldness, clitoral enlargement))
