P aeruginosa (☆cystic fibrosis pneumonia (adult, child→ S aureus), contact lenses)
Nontypeable (unencapsulated) H influenza (most common cause of mucosal infections like ☆otitis media, conjunctivitis, sinusitis) microbiologyUWorld Jul 10, 2020, 4:38 AM HirotoShishido
inflammatory breast cancerDermal lymphatic space invasion→ breast pain with warm, swollen, erythematous skin around exaggerated hair follicles, ☆peau d’orange.
Poor prognosis (50% survival at 5 years). Often mistaken for mastitis or Paget disease. Usually ☆lacks a palpable mass.
"inflammatory" is a misnomer because the classic skin findings are not due to infection but are instead caused by cancerous cells obstructing lymphatic drainage after spreading to the dermal lymphatic spaces. breast surgeryOBGYUWorld Jul 9, 2020, 8:36 AM HirotoShishido
invasive lobular (breast) carcinoma↓E-cadherin expression(diffuse gastric cancer)→ orderly row of cells (“single file”) and no duct formation. Often lacks desmoplastic response.
comedocarcinomaSubtype of DCIS(dultal carcinoma in situ). Cells have ☆high-grade nuclei with extensive central necrosis and dystrophic calcification breast surgeryOBGYUWorld Jul 9, 2020, 8:23 AM HirotoShishido
OCPs/ PCOS to gynecologic malignancyOCPs → ↑cervical cancer, ↑breast cancer ↓ovarian cancer
